Thomas M. Campbell, MD

12 Frightening Facts About Milk

A large observational cohort study[1] in Sweden found that women consuming more than 3 glasses of milk a day had almost twice the mortality over 20 years compared to those women consuming less than one glass a day.

Intervention Trials, Campbell’s Office Hours Webinar

The following video is a highlight from our October 2014 Campbell’s Office Hours Webinar provided for current and past students.

How Sweet is a Sweet Potato? Pretty Sweet!

Sweet potatoes are a super food that I have only recently come to appreciate. When preparing my lecture on heart disease epidemiology for our new eCornell course, I found reports of several traditional cultures known for avoiding heart disease that subsist largely on this delicious tuber. In fact, a 1978 paper[1] cited a dietary survey finding that sweet potatoes supplied about 90% of total calorie intake in the traditional subsistence culture of the Papua New Guinea highlanders. 90%! Sinnett and Whyte write, “Indeed, non-tuberous vegetables accounted for less than 5% of the food consumed, while the intake of meat was negligible.” There was no evidence of malnutrition from this diet and no evidence for hypertensive heart disease.

Here are some facts to chew on. If HALF of your diet was solely baked sweet potatoes with no salt, you would get all [...]

Analysis of the Latest Low-Carb, Low-Fat Study

The following video is a highlight from our first live Campbell’s Office Hours Webinar provided for current and past students.
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Are Smoothies Good or Bad?

In medical school, when time was shorter than short and I lived alone, I would periodically get concerned that I wasn’t eating enough leafy greens, because I wasn’t.
  • The APOC3 Mutation Story
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    A Goal of (Profitable) Mediocrity in the Fight Against Heart Disease: The APOC3 Mutation Story.

A Goal of (Profitable) Mediocrity in the Fight Against Heart Disease: The APOC3 Mutation Story.

On June 19th, an article in the New York Times titled, “In Single Gene, a Path to Fight Heart Attacks,” unintentionally highlighted the modern promise and the utter failure of our medical system, both at the same time. It describes the findings from two recent studies on the genetic causes of high triglycerides. Both of these studies were large, well-conducted, and published in a highly regarded journal with extensive press coverage. The NYT article was on the front page “above the fold”.

The findings of the two studies, utilizing the genetic analysis of almost 200,000 people, showed that there are four relatively rare genetic mutations on a gene coding for apolipoprotein C3 (APOC3) that are linked to low triglyceride levels. Although there is uncertainty regarding how triglycerides are involved in heart disease, it is quite clear that high triglycerides are associated with increased risk.

The important result from these studies is that people with the mutations had not only lower triglycerides, but also about a 40% lower risk of coronary heart disease.

Research of this type could never have been done 50 years ago. It embodies remarkable medical and technological advances of recent years. Further, this research is intellectually stimulating and obviously relevant to heart disease, our number one killer. I have no doubt scientists and clinicians directed the studies with an eye toward what they genuinely feel is in the public’s best interest.

And yet I am troubled.